VPS13A and McLeod neuroacanthocytosis syndrome: Additional studies support this interaction: Erythrocytes of McLeod syndrome showed that lack of Xk leads to a loss of Vsp13a in their membrane [19] and overexpression of Xk has been shown to relocalize overexpressed Vps13a from contacts between lipid droplets and the ER to the entirety of the ER together with Xk in HEK293T cells [20].