INS and Insulin resistance: Previous research has demonstrated that coenzyme Q10 is a regulator of insulin and adiponectin receptors, phosphatidylinositol kinase 3, tyrosine kinase, and glucose transporters, suggesting that the antioxidant can enhance insulin sensitivity.[47] Omega-3 fatty acids may improve insulin sensitivity by inhibiting proinflammatory mediators and decreasing nuclear factor-kappa B activation, thereby reversing insulin resistance.[48]