A number of studies indicate that genetic variation plays an important role in the occurrence and development of diseases,[20,21] in which MCP-1 single nucleotide polymorphism (SNP) has been widely reported to be related to T2DM, sepsis, and other inflammatory conditions.[22] In this study, we compared the allele frequency and genotype frequency of MCP-1 rs1024611 between the T2DM with sepsis group and the T2DM control in a case–control association analysis. The gene discussed is CCL2; the disease is type 2 diabetes mellitus.