Pro‐inflammatory cytokines, such as interleukin 6 (IL‐6), are known to sensitize peripheral nerve endings (Schaible, 2014), and one study has suggested that IL‐6 level is increased by synovitis and the presence of type 2 diabetes in patients with knee OA (Eitner et al., 2017). The gene discussed is IL6; the disease is type 2 diabetes mellitus.