Among DC subsets, cDC1 have superior cross‐presentation capacity and, in fact, cross‐presentation by cDC1 was shown to be necessary for CD8+ T‐cell‐mediated tumor rejection in multiple studies (Perez & De Palma, 2019; Cabeza‐Cabrerizo et al, 2021). This evidence concerns the gene MPPE1 and neoplasm.