Although Miro2 did not have an effect on tumor cell invasion in the model of syntaphilin knock-down cells, it did effect, together with Miro1, mitochondrial trafficking and invasion of cancer cells in the model of stress induced tumor cell invasion, indicating a mechanism independent of the syntaphilin protein (Caino et al., 2016; Lopez-Domenech et al., 2018). The gene discussed is RHOT2; the disease is cancer.