To identify the independent predictors, statistically significant variables from the univariate model were determined in the multiple stepwise logistic regression model, which ultimately reveled that ALB [odds ratio (OR) 0.79, 95% confidence interval (CI) 0.69–0.89, p < 0.001], TBIL (OR 0.61, 95% CI 0.5–0.75, p < 0.001), and UA (OR 0.97, 95% CI 0.96–0.99, p = 0.014) were independently associated with migraine (Table 3). This evidence concerns the gene ALB and migraine disorder.