In addition, we found some bridging genes between symAD vs. control and symAD vs. AsymAD that were overlapping in these two comparative groups: RPS6, RPS18, RPS3A, RPS24, and RPL9. Whereas AsymAD vs. control groups showed unique gene signatures, suggesting the onset of AD progression to be exclusively restricted to AsymAD. The gene discussed is RPS3A; the disease is Alzheimer disease.