Overall, 3 variants from the AR gene and 2 variants from ER-α were genotyped - ARrs137852568, ARrs137852599 and AR rs137852563, and ER-α rs796065354 and ER-αrs104893956- using amplification refractory mutation system methods.Results: The obtained results indicated a significant association between AR rs1378525568 TT genotype as well as AR rs137852599 C allele with odds of male infertility (OR: 0.433, CI: 0.197-0.951 and OR: 0.545, CI: 0.304-0.978, respectively). This evidence concerns the gene AR and male infertility.