In research on the correlation between g_Helicobacter and AD, it was found that intraperitoneal injection of Helicobacter can directly induce the overexpression of Aβ and hyperphosphorylation of tau in the brains of rats; furthermore, the LPS produced by g_Helicobacter has been associated with autoimmune complications of neuropathy [61]. This evidence concerns the gene MAPT and Alzheimer disease.