The results showed that TGF-β1 induced the expression levels of FN and caspase-3 in the NRK-52E cells that were significantly increased, while DSS and rapamycin could significantly inhibit the increase of these proteins (Figure 2); thus, we believe that DSS has a certain therapeutic effect on renal fibrosis. The gene discussed is TGFB1; the disease is renal fibrosis.