To date, studies have reported the role of RBBP7 in several diseases, such as Alzheimer's disease [33] and Wilms Tumor 1 [34], while our results of single-gene GSEA showed that “Fc gamma R-mediated phagocytosis” pathway was significantly enriched in BKVN samples with higher expression levels of RBBP7, which set the foundation for researches of RBBP7 in virus-associated diseases, also in BKVN. This evidence concerns the gene RBBP7 and early-onset autosomal dominant Alzheimer disease.