DMRT3 and cerebral palsy: Since Dmrt3 participates in the specification of spinal cord dI6 interneurons [mutations in the Dmrt3 gene affects locomotion in horses and mice (Andersson et al., 2012)], and dmrt3 is involved in cortical development (Konno et al., 2019), if conserved in these features, DMRT3 could contribute to motor symptoms in cerebral palsy patients as a consequence of impaired development of the motor cortex and dysfunctional locomotion circuits in the spinal cord.