ARHGDIA and asthma: Gene set enrichment analysis using IPA presented the lung leukocyte clusters, which showed decreased activation of pathways of RHOGDI (Rho GDP-dissociation inhibitor) signaling, apoptosis signaling, TWEAK (TNF-related weak inducer of apoptosis) signaling, IL-17 signaling, and PAK signaling, which regulate cellular function including stress-related response and allergic airway diseases 10, 18, 41), during severe asthma in the miR-155KO mice.