CALM1 and rheumatoid arthritis: (81) used a novel drug-coupled antibody (CD64-CaMi) against the IgG high-affinity receptor (FcgammaRI) to culture monocytes in the peripheral blood and synovial fluid of RA patients, where CD64-CaMi was shown to induce SM death along with the effective inhibition of pro-inflammatory Th1 cytokine production.