EMP1 and breast cancer: Of note, it was further found that lower gene expression levels of TPST1 and EMP1, two genes from the FARG signature, were correlated with the immunotherapy response (p < 0.01, Figure 10D) among BC patients from the IMvigor210 cohort, whereas FGFR3 expression was not found to be significantly associated with immunotherapy response in the IMvigor210 cohort (p = 0.24, Supplementary Figure 7).