Thus, density numbers of infiltrating CD8+, CD4+, and FOXP3+ T-cell lymphocytes, CD20+ T-cell lymphocytes, and CD68+ and CD163+ macrophages were separately evaluated in both the tumor nests and surrounding stroma, and the mean numbers were correlated with the mean values for NLR, PLR, SII and LMR (Table 6). This evidence concerns the gene CD4 and neoplasm.