Furthermore, B cells can be meaningful sources of IL-10 during schistosomiasis (29, 34), quantification of which would require alternative approaches, such as stimulation via TLRs and CD40 (75), or the use of IL-10 reporter mice, which constitute an improved tool for visualisation of which cell types contribute to the IL-10 pool (76). The gene discussed is IL10; the disease is schistosomiasis.