CXCL10 and infection: As early as wk 3 post infection we were able to observe distinct transcriptional profiles in infected mice compared to naïve controls (Figures 4A, B) including increased expression of chemokines (Cxcl9 and Cxcl10) and genes associated with MHCII expression (H2-Aa, H2-Ab1 and H2-Eb1) (Figure 4B).