Likely, the elevated plasma IL-10 (optimal threshold >11.59 pg/mL) inhibits antigen presentation, decreasing ex vivo LPS-stimulated TNF-α production capacity (optimal threshold < 505.8 pg/mL) leaving the individual highly susceptible to infections by decreasing T cell immunity (7, 27, 47, 49, 50). This evidence concerns the gene IL10 and infection.