TXN and gastric cancer: In addition, the results suggested that High-Trx1 HP can have a stronger influence on the gastric epithelial cell line, in which HP Trx1 can promote the apoptosis of human normal gastric epithelial cell line GES-1 and the proliferation of human gastric cancer cell line BGC823, and the balance between proliferation and apoptosis of gastric epithelial cell line is disturbed, which further suggested that HP Trx1 may promote the occurrence and development of gastric cancer [8].