ACTA1 and atrial fibrillation: The overexpression of miR-27b-3p can regulate the Wnt/β-Catenin signaling pathway reducing the occurrence and duration of AF, reducing MF and increasing the expression of connexin 43, and also reducing the expression of collagen-I, α-SMA, Collagen-III, TGF-β1, Wnt3a, and p-β-catenin (40).