Moreover, although the expression of IGKV1-8, PMP22, PIK3R6, KCNMB2-AS1, and TCL6 in CTEPH may not be sex-specific, whether patients with CTEPH have specific profile in gender needs to be further studied by expanding the sample. The gene discussed is KCNMB2; the disease is chronic thromboembolic pulmonary hypertension.