The results of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) database shown in Figure 2(c) indicated that the expression of VDAC1 protein increased in primary tumors, including breast cancer, ovarian cancer, colon cancer, UCEC, and LUAD, and reduced in clear cell RCC, compared with normal tissues (P < 0.001). This evidence concerns the gene VDAC1 and malignant colon neoplasm.