AKT1 and infection: Inhibition of the PI3K-Akt-mTOR signaling pathway can affect post-infection inflammatory, apoptotic, and autophagic responses, protecting host cells from various pathogens, including Mycobacterium tuberculosis (Lachmandas et al., 2016), Legionella pneumophila (Abshire et al., 2016), and Listeria monocytogenes (Gessain et al., 2015).