ZFPM2 and Pulmonic stenosis: In FOG2 knockout mouse embryos, a thin ventricular myocardium, common atrioventricular canal, tetralogy of Fallot malformation including ventricular septal defect, pulmonary stenosis, misplaced aorta, and an absence of coronary vasculature have all been reported (Tevosian et al., 2000; Hirai et al., 2004).