PHOSPHO1 transcript was increased in the liver of nonalcoholic steatohepatitis patients (Liu et al., 2011) and diminished in the liver of hepatitis mice, myocardial tissue of mice with left ventricular hypertrophy (Mirotsou et al., 2006), and muscle of mice with type 1 diabetes mellitus (Lehti et al., 2006; Barrett et al., 2013). Here, PHOSPHO1 is linked to diabetes mellitus.