Second, through meta-analysis of primary CRC and metastatic foci, we also confirmed that LPL, CD36, LDLR, FASN, FABP1, SCD, ABCA1, APOA1, AGPAT1, and SREBF1 expression levels were associated with lung or liver tropisms, suggesting that metabolic alterations help dictate, among other alterations, specific organotropisms in CRC patients. Here, LDLR is linked to colorectal carcinoma.