PTPN1 and hepatocellular carcinoma: In hepatocellular carcinoma, miR-122 and miR-206 target the 3’ untranslated region (3’ UTR) of PTPN1 mRNA and induce its degradation (218, 219), while miR-125a-5p suppresses PTPN1 expression via the MAPK signaling pathway (220), both of which ultimately alleviated the progression of hepatocellular carcinoma.