Twelve chemokines, including IL10, CCL2, CCL3, CCL4, CCL11, CCL19, CCL22, CCL27, CXCL1, CXCL12, and CXCL16, were upregulated in the TD group compared with the T group (Figure 6C). This evidence concerns the gene CXCL1 and thanatophoric dysplasia.