Gene set enrichment analysis (GSEA) showed that genes with expression changes (fold change > 1.5) were significantly associated with cancer development and metastasis, such as the NF−κB pathway (Figure 7A and Supplementary Table 7A, B), supporting the role of CCDC102B in breast cancer cell proliferation and metastasis. This evidence concerns the gene NFKB1 and breast carcinoma.