Based on the TMA data, we analyzed the correlation between CCDC102B expression and the prognosis of breast cancer patients, which showed that CCDC102B was an independent predictive factor of both recurrence-free survival (RFS) and overall survival (OS) (P=0.009 and P=0.002, respectively, Supplementary Tables 2B, C). The gene discussed is CCDC102B; the disease is breast cancer.