RB1 and anemia: However, there were 50 (25.38%), 13 (6.60%), and 1 (0.51%) children with Rb who had a cross-level increase in the degree of bone marrow suppression by one, two, and three grades, respectively (Figure 3B).After IAC, the proportion of anemia and bone marrow suppression in children with Rb who developed worse conditions were 41.24% and 32.49%.