More risk factors were screened in women after adjustment of age and BMI, including β-CTx, fracture history, height loss (>3cm), PTH, OST, age of menarche, ALP, PINP; while grip strength of each hand, age of menopause, duration of menstruation, and steatohepatitis history were negatively correlated with osteoporosis. This evidence concerns the gene PTH and osteoporosis.