Overexpression of PLK1 was observed in prostate cancer (Weichert et al., 2004), colorectal cancer (Takahashi et al., 2003), neuroblastomas (Ramani et al., 2015), and rectal cancer (Tut et al., 2015) and was associated with poor prognosis. This evidence concerns the gene PLK1 and Familial prostate cancer.