Downregulation of LDOC1 was discovered in various tumor tissues, such as the lung (Lee et al., 2015; Lee et al., 2019), colorectum (Jiang et al., 2019), cervix (Buchholtz et al., 2013; Chen and Wang, 2019), vulva (Wanka et al., 2020), pancreas (Nagasaki et al., 2003), and papillary thyroid (Zhao et al., 2015). Here, LDOC1 is linked to neoplasm.