TAFAZZIN and central nervous system cancer: This applies also to C6 rat glioma cells where the knock-out of tafazzin has been shown previously to alter CL composition and, consequently, to compromise mitochondrial respiration, and cellular proliferation (Murke et al., 2016; Ohlig et al., 2018; Gurtler et al., 2019; Schild et al., 2020).