CD274 and Chagas disease: Besides, the top 10 enriched KEGG terms were as follows (Figure 3B): Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Th17 cell differentiation, PD-L1 expression, and PD-1 checkpoint pathway in cancer, Natural killer cell-mediated cytotoxicity, Hematopoietic cell lineage, Chagas disease, Human immunodeficiency virus one infection, Measles, Fc epsilon RI signaling pathway.