TNF and Insulin resistance: S. baicalensis can help in improving insulin resistance by decreasing the levels of fasting and postprandial GLU, fasting insulin, homeostatic model assessment for insulin resistance, TGs, and LDL-Chol, and preventing inflammation by lowering the expression of inflammatory gene (TNF-α, IFN-γ, and F4/80) in HFD-induced insulin-resistant mice [89].