−Most cytotoxic extract was the methanol one with the greatest effect on p53 in all cancers−Concentration of 15 μM (butanolic extract) was considered optimal for treating cervical and breast cancer cell lines, based on the IC50 values in all the extracts.−T. violacea extracts inhibit cell proliferation in a cell line- and dose-dependent manner. The gene discussed is TP53; the disease is breast cancer.