Zheng Li et al. illustrated that HIF1α can promote angiogenesis in gastric cancer, and this process can be promoted by Natriuretic peptide receptor A (NPRA), NPRA is the most important receptor of atrial natriuretic peptide (ANP), NPRA functions significantly in promoting GC development and progression [78] (Table 5). Here, HIF1A is linked to gastric cancer.