ACHE and Alzheimer disease: The incorporation of AChE into Alzheimer’s amyloid aggregates results in the formation of stable complexes that change the biochemical and pharmacological properties of the enzyme, and cause an increase in the neurotoxicity of the amyloid-β fibrils, suggesting that AChE could play a pathogenic role in AD by influencing the process leading to amyloid toxicity and the appearance of AD [54].