When AnxA1 level was measured in the blood and CSF of patients with AD and behavioral variant of frontotemporal dementia (bvFTD), reduced plasma levels of AnxA1 were observed in bvFTD compared to AD and controls, while no difference was shown in the CSF; moreover, a significant cleavage of AnxA1 in PBMCs in both dementia groups was shown [89]. Here, ANXA1 is linked to dementia.