Kanglaite pretreatment can not only increase the effect of taxol on colorectal cancer and cisplatin on HepG2 cells by inhibiting the CKLF1-mediated NF-κB pathway [157,158], but also inhibits tumor necrosis factor-alpha-mediated epithelial mesenchymal transition in colorectal cancer cell lines by inhibiting NF-κΒ [47]. This evidence concerns the gene TNF and colorectal cancer.