These properties include: (a) Several types of cancer tissues show abnormal amyloid-like aggregates of misfolded p53 [32]; (b) p53 amyloid formation leads to cellular pro-metastatic gain-of-function [36]; (c) p53 amyloid-fibrils seed misfolding and aggregation when internalized in cells [37], and (d) p53 amyloid formation in cells impairs its transcriptional regulation function [34]. This evidence concerns the gene TP53 and cancer.