DDMP-induced apoptosis in colon cancer cells (SW620 and HCT116) via the modulation of the activity of NF-KB, where it suppressed the anti-apoptotic genes (BCL2), whereas it induced the expression of the apoptotic genes (BAX, cleaved caspase-3 and cleaved PARP) [24]. The gene discussed is CASP3; the disease is malignant colon neoplasm.