In addition to its effects strictly exerted in response to DNA damage, SIRT1 induces an increase in lifespan by protecting against the onset of age-related diseases such as diabetes mellitus [12], hepatic steatosis [13], cardiovascular diseases, atherosclerosis [14], osteoporosis [15], and neurodegenerative disorders [16]. This evidence concerns the gene SIRT1 and Hepatic steatosis.