CASP3 and myelodysplastic syndrome: The mean cleaved caspase-3 grade was highest in MDS patients, followed by ICUS patients and HCs (2.70, 95% CI: 2.56–2.85 vs. 2.19, 95% CI: 1.85–2.54 vs. 1.45, 95% CI: 1.17–1.73, p < 0.001, respectively) (Figure 1A).