In a COVID-19 cohort, the depletion of several bacterial species (B. adolescentis, E. rectale and F. prausnitzii, known to play immunomodulatory roles in the human GI system) was linked to increased plasma concentrations of TNF-α, CXCL10, CCL2 and IL-10 [65]. The gene discussed is CXCL10; the disease is COVID-19.