Attenuated oxidative damage, namely increased GPx activity and decreased MDA levels and protein carbonylsInhibited glial activation; reduced the levels of TNF-α, IL-1β, and IL-6; and prevented neuronal damageAlleviated ACh depletion, ChAT inhibition, and AChE activationImproved cognitive deficits. This evidence concerns the gene IL1B and Cognitive impairment.