Considering the fact that both IP-10 and MCP-3 peak only late in the course of subarachnoid hemorrhage [10], and both have a potent chemoattractant for inflammatory cells, the association of their early high levels with poor outcome, as we found in our study, suggests a prominent role of inflammation in the pathophysiology of early aSAH. This evidence concerns the gene CXCL10 and subarachnoid hemorrhage.