GSTM2 and benign prostatic hyperplasia: Similarly, under nutritional stress, while methylation values for CYP6AY1, CYP6ER1-CpG1, CYP6ER1-CpG2, and Est exhibited variations between stress-exposed BPH and control samples, and also across life stages, InR2 and Gstm2 did not show any change (Figure 4B and Figure 5B).